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About GLP-1
What You need to know about GLP-1 Medications.
GLP-1
What Are GLP-1 Medications?
GLP-1 medications like Semaglutide and Tirzepatide help with weight loss, lower blood sugar levels, reduce A1C, and decrease the risk of heart issues. These medications mimic a natural hormone that helps with digestion, suppresses appetite, and slows the rate food leaves the stomach, helping you feel full longer. They are most effective when combined with regular exercise and a healthy diet.
Benefits:
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Promotes weight loss
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Helps maintain a healthy weight
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Lowers blood sugar and A1C levels
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Reduces the risk of heart issues
GLP-1
What to Expect
Initial Effects: Some may feel a decrease in appetite within a few days, but for most, it may take longer.
Dosage Adjustment: You’ll start with a lower dose for 4 weeks to minimize side effects, then gradually increase to a maintenance dose for the best results.
Side Effects: The most common are gastrointestinal (GI) issues like nausea, constipation, diarrhea, and heartburn. These side effects are more common when starting or increasing the dose but tend to lessen over time.
Storage Instructions:
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Keep the medication in the refrigerator (36°F to 40°F / 2°C to 4°C), but let it warm to room temperature before use.
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Protect from light and heat. Do not freeze.
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Store it safely out of reach of children and pets.
Potential Risks:
Common Side Effects: GI symptoms (nausea, vomiting, diarrhea, etc.), headache, and dry mouth.
Severe Reactions: If you experience a rash, difficulty breathing, or swelling, call 911 immediately.
Low Blood Sugar: Symptoms include dizziness, confusion, sweating, or rapid heartbeat. If you notice these, stop taking the medication and contact your doctor right away.
Important Note
It’s essential to consult with your healthcare provider before starting GLP-1 medications to ensure they’re right for you and to discuss any concerns you may have.
Basic Principles
Eat Real Foods
Focus on whole, unprocessed foods—think lean proteins, colorful vegetables, fruits, and whole grains.
Protein First
Whether you prefer three meals a day or smaller, more frequent meals, be consistent to help regulate appetite and blood sugar.
Stay Hydrated
Aim for 8–10 cups of water daily. Medications like semaglutide /tirzepatide can sometimes decrease thirst, so be intentional about drinking water.
Moderate Portions
Even healthy foods can cause weight gain if eaten in excess. Start getting familiar with recommended portion sizes (e.g., a palm-sized portion of protein, a fist-sized portion of carbs).
Consistent Meal Pattern
Whether you prefer three meals a day or smaller, more frequent meals, be consistent to help regulate appetite and blood sugar.
Health Benefits of Semaglutide and Tirzepatide (Beyond Weight Loss)
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Improved Blood Sugar Control
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Helps regulate insulin and lower fasting blood glucose
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Reduces A1C levels by up to 2.5% in individuals with type 2 diabetes
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Supports more stable energy levels and fewer blood sugar crashes
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Cardiovascular Protection
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Lowers blood pressure in many patients
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Improves cholesterol levels (reduces LDL and triglycerides, increases HDL)
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Semaglutide is FDA-approved to reduce the risk of major cardiovascular events in adults with type 2 diabetes and heart disease
03
Reduced Inflammation
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Lowers inflammatory markers such as CRP
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May reduce risk of chronic inflammatory diseases (e.g., arthritis, cardiovascular disease)
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Better Digestive Regulation
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Slows gastric emptying, promoting better digestion and glucose absorption
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Helps control post-meal blood sugar spikes
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Enhanced Liver Function
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Reduces liver fat accumulation
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Supports improvement in non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH)
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Hormonal Balance & Appetite Regulation
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Regulates hunger hormones like GLP-1 and GIP (Tirzepatide)
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Increases satiety (feeling full) and reduces food cravings, even after reaching goal weight
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Cognitive and Mental Health Benefits
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Linked to improved mental clarity and reduced brain fog
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Some studies suggest potential protective effects against cognitive decline and Alzheimer's (ongoing research)
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Many users report improved mood and self-confidence as a result of overall metabolic health improvement
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Sleep & Energy Improvements
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Improved sleep quality due to better metabolic function
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Reduced sleep apnea severity in overweight individuals
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Increased daily energy and reduced fatigue
FDA-Backed Safety and Efficacy
Both Semaglutide and Tirzepatide have undergone rigorous clinical testing and have been reviewed and authorized by the U.S. Food and Drug Administration (FDA) for the following:
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Semaglutide is FDA-approved for weight management and type 2 diabetes, with specific approval for reducing cardiovascular risk in diabetic patients.
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Tirzepatide is FDA-approved for type 2 diabetes and received Fast Track designation for chronic weight management due to its significant efficacy.
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The health benefits listed above are based on peer-reviewed studies and data submitted to the FDA as part of the approval process.
These medications are considered safe and effective when prescribed and monitored by a licensed healthcare provider.